the open source VC database
Massachusetts HQ VCs
These firms list Massachusetts as their headquarters location. Headquarters indicates where a firm is based; it does not define the firm's investment territory.
includes only:HQ: Massachusetts
| .406 Ventures406ventures.com | Can Lead | $1m – $10m$1-3m · $3M - $10M | — | Specialist | Healthtech / Digital Health, Cybersecurity | Massachusetts | $265M Fund V | 2024 | Liam Donohue, Graham Brooks, Payal Agrawal Divakaran, Greg Dracon, Trip Hofer, Kathryn Taylor Reddy, Kevin Wang, Rebecca Redfield, Austin Kwoun | contact@406ventures.com | |
| 186 Venturesverified186ventures.com | Can Lead | $500k-1m | 5–10%5-7% · 7-10% | Generalist | — | Massachusetts | $37M | 2022 | Giuseppe Stuto, Julian Fialkow | hello@186ventures.com | |
| Accelr8accelr8.com | Mostly Lead | — | — | Specialist | Climate / Energy, Industrial / Manufacturing, Food / Agriculture, PropTech / Construction | Massachusetts | — | — | Dwight Poler, Ryan Macpherson, Louis Kang, Megan Phelan | info@accelr8.com | |
| Accompliceaccomplice.co | Can Lead | $250k – $3m$250-500k · $500k-1m · $1-3m | — | Generalist | — | Massachusetts | $405M final fund | 2022 | Jeff Fagnan, Ryan Moore, Saneel S., Samuel Clemens, Sarah Downey | hello@accomplice.co | |
| Advancit Capitaladvancitcapital.com | Mostly Follow | — | — | Specialist | Crypto / Web3, Gaming / Media / Sports | Massachusetts | — | — | Shari Redstone, Jason Ostheimer | info@advancitcap.com | |
| Algorand Venturesalgorand.co | Mostly Follow | — | — | Specialist | Crypto / Web3 | Massachusetts | — | — | Amar Odedra | contact@algorand.com | |
| AMR Action Fundamractionfund.com | Can Lead | — | — | Specialist | Life Sciences | Massachusetts | $1B+ target | 2020 | Henry Skinner, Martin Heidecker, Junjun Gao, Carly Levine, Henni-Karoliina Ropponen, Isabella Santi | https://www.amractionfund.com/investments/#radarForm | |
| Argon Venturesargon.vc | Mostly Lead | $250-500k | — | Generalist | — | Massachusetts | — | — | Bob Mason, Andy Feinberg, | info@argon.vc | |
| Atlas Ventureatlasventure.com | Mostly Lead | — | 7–10%7-10% | Specialist | Life Sciences | Massachusetts | $450M Fund XIV | 2026 | David Grayzel, Jason Rhodes, Jean-Francois Formela, Michael Gladstone, Kevin Bitterman, Bruce Booth, Peter Barrett, Jernej Godec, Aimee Raleigh, Maurizio Fazio, Julia Pian, Justin Feng, Stella Paffenholz | lifesciences@atlasventure.com | |
| Atreides Managementatreidesmgmt.com | — | — | — | Generalist | — | Massachusetts | — | — | Gavin Baker, James Stanzler, Neil Desai, Andrew Perlman | info@atreidesmgmt.com | |
| Azolla Venturesazollaventures.com | Can Lead | — | — | Specialist | Climate / Energy, Deep Tech, Industrial / Manufacturing | Massachusetts | $239M — Azolla Ventures Fund I blended fund | — | — | info@azollaventures.com | |
| Battery Venturesbattery.com | Mostly Lead | $10m – $30m+$10M - $30M · >$30M | 7–10%7-10% | Generalist | — | Massachusetts | $3.25B (Battery Ventures XV) | — | Chelsea Stoner, Dharmesh Thakker, Jesse Feldman, Michael Brown, Morad Elhafed, Neeraj Agrawal, Roger Lee, Russell Fleischer, Zack Smotherman, Barak Schoster, Brandon Gleklen, Dallin Bills, Dillon Joyce, Justin Rosner, Roland Anderson, Satoshi Harris-Koizumi | dallin@battery.com | |
| Blindspot Venturesblindspot.vc | — | — | — | Specialist | Infrastructure / Developer Tools, Deep Tech, Industrial / Manufacturing, Healthtech / Digital Health, Life Sciences | Massachusetts | — | — | Ahmed Hentati, Hassan Dayekh, Dalil Abdellaoui | Hello@Blindspot.vc | |
| Bramalea Partnersbramaleapartners.com | Can Lead | $3m – $30m$3M - $10M · $10M - $30M | — | Specialist | Enterprise Software | Massachusetts | — | — | — | — | |
| Brewer Lane Venturesbrewerlane.com | Mostly Follow | — | — | Specialist | Fintech, Healthtech / Digital Health | Massachusetts | $213M Fund II | 2024 | John Kim, Chris Downer, Rohan Malhotra, Martha Notaras, Kaitlin Derry, Jae Yoon | info@brewerlane.com | |
| Broadview Venturesbroadviewventures.org | Mostly Lead | — | — | Specialist | Life Sciences, Healthtech / Digital Health | Massachusetts | — | — | Thomas Needham, Daniel Gottlieb, Kelly Krajnik, Christopher de Souza, Benjamin Kreitman, Hewmun Lau, David Prim | bkreitman@broadviewventures.org | |
| Building Venturesbuildingventures.com | Mostly Lead | — | — | Specialist | PropTech / Construction | Massachusetts | — | — | Jesse Devitte, Travis Connors, Heather Widman, Allen Preger, Lucas Turner-Owens, Mayra Arntz | — | |
| Bullhorn Venturesbullhorn.com | — | — | — | Specialist | Enterprise Software, Education / Future of Work | Massachusetts | $20M | 2022 | — | https://www.bullhorn.com/apply-to-bullhorn-ventures/ | |
| Castle Island Venturescastleisland.vc | Mostly Lead | — | — | Specialist | Crypto / Web3, Fintech | Massachusetts | $250M — Castle Island Ventures III | 2021 | Matthew Walsh, Nic Carter, Sean Judge, Rich Sgalardi, Wyatt Khosrowshahi, Henry Harris | info@castleisland.vc | |
| Clean Energy Venturescleanenergyventures.com | — | — | — | Specialist | Climate / Energy | Massachusetts | $305M Fund II (closed); $415M AUM | — | Dan Goldman, David S. Miller, Temple Fennell, Cooper Bates, Maya Bhat, Yi Jean Chow, Matt Cohen, Shanbor Gupta, Louis Schick, Max Werny, Wynston Reed, Amy Zhao | info@cleanenergyventures.com | |
| Companyon Venturescompanyon.vc | Mostly Follow | $1-3m | — | Specialist | Enterprise Software, Fintech | Massachusetts | — | — | Tom Lazay, Firas Raouf, Ronny Chatterjee, Andrew Berg | pitches@companyon.vc | |
| Convergeconverge.vc | — | — | — | Specialist | Enterprise Software, Cybersecurity, Infrastructure / Developer Tools, Industrial / Manufacturing, Deep Tech | Massachusetts | — | — | Nilanjana Bhowmik, Maia Heymann, Anshu Agarwal, James Falkoff, Lourenco Belleau | — | |
| Creacion Venturescreacionventures.com | — | — | — | Specialist | Life Sciences | Massachusetts | — | — | — | — | |
| Cure Venturescurevc.com | Can Lead | — | — | Specialist | Life Sciences, Deep Tech | Massachusetts | $350M — Cure Ventures Fund I, L.P. | — | — | info@curevc.com | |
| Cybernetix Venturescybernetix.vc | — | — | — | Specialist | Deep Tech, Industrial / Manufacturing, Supply Chain / Logistics / Mobility, PropTech / Construction, Healthtech / Digital Health, Food / Agriculture, Climate / Energy, Cybersecurity | Massachusetts | — | — | Fady Saad, Mark Martin, Jackson Saunders | — | |
| Double Point Venturesdoublepointventures.com | Can Lead | — | — | Specialist | Life Sciences, Healthtech / Digital Health | Massachusetts | — | — | Campbell Murray, Daniel Yadegar | eadoctordan@gmail.com | |
| Drive by DraftKingsdrivebydraftkings.com | Mostly Follow | — | — | Specialist | Gaming / Media / Sports | Massachusetts | — | — | Meredith Mcpherron, Kiki Mills Johnston, Jon Von Deylen, Josh Wasserman | info@drivebydraftkings.com | |
| Elephantelephantvc.com | — | — | — | Generalist | — | Massachusetts | — | — | Julie Effron, Peter Fallon | pat@elephantvc.com | |
| Encoded Venturesencoded.vc | Can Lead | $250k – $1m$250-500k · $500k-1m | — | Specialist | Infrastructure / Developer Tools | Massachusetts | — | — | Alex Benik | alex@encoded.vc | |
| F-Prime Capitalfprimecapital.com | Mostly Lead | $1m – $30m+$1-3m · $3M - $10M · $10M - $30M · >$30M | 7–10%7-10% | Specialist | Life Sciences, Healthtech / Digital Health, Enterprise Software, Fintech, Crypto / Web3 | Massachusetts | — | — | Amber Cai, Ben Gorman, Carlos Bustamante, Eric Blatte, Hannah Arnold, Harlan Krumholz, Jay Farber, John Vigeant, Josh Feinblum, Jackson Wilkinson, Mihir Shah, Mona Vernon, Muzammil Mansuri, Sam Bisbee, Sandor Palfy, Sanjay Aggarwal, Stephen Knight, Steve Schultz, Tristan Zajonc | info@fprimecapital.com | |
| Fast Track Initiative, Inc.us.fasttrackinitiative.com | — | — | — | Specialist | Life Sciences, Healthtech / Digital Health | Massachusetts | — | — | Hiromichi Kimura, Tomohiro Anzai | message@fti-jp.com | |
| Fifth Down Capitalfifthdown.com | — | — | — | Generalist | — | Massachusetts | — | — | Andrew Spellman, Janki Gandhi, Anthony Mulrain, Jerod Mayo, James Boyd, JP Steers, Alan Swierczynski, David Greenberg | — | |
| Fine Structure Venturefinestructure.vc | Mostly Lead | — | — | Specialist | Deep Tech | Massachusetts | — | — | Jennifer Uhrig, Shyam Kamadolli, Amrit Jalan, David Needell, Dionis Minev, Tobias Egle | info@finestructure.vc | |
| First Star Venturesfirststar.vc | Mostly Follow | — | — | Specialist | Deep Tech, Life Sciences, Crypto / Web3 | Massachusetts | — | — | Drew Volpe, Millie Liu, Teddy Blank | contact@firststar.vc | |
| Flagship Pioneeringflagshippioneering.com | Can Lead | — | — | Specialist | Life Sciences, Climate / Energy, Industrial / Manufacturing, Other | Massachusetts | $2.6B Raised into Fund VIII | — | — | — | |
| Flare Capital Partnersverifiedflarecapital.com | Mostly Lead | $1m – $30m$1-3m · $3M - $10M · $10M - $30M | 10%+10-12% · > 12% | Specialist | Healthtech / Digital Health | Massachusetts | — | — | Michael Greeley, Ian Chiang, Parth Desai, Dan Gebremedhin, Victor Lanio, Margaret Malone, Todd Schwarzinger, Tara Sullivan, Jonathon George, Alyssa Tsenter, Sara Hoffman | bill@flarecapital.com | |
| Flint Capitalflintcap.com | Mostly Follow | — | — | Specialist | Enterprise Software, Fintech, Healthtech / Digital Health, Commerce / Marketplaces | Massachusetts | — | — | Dmitry Smirnov, Sergey Gribov, Andrew Gershfeld, David Feldman, Elena Gantvarg | info@flintcap.com | |
| Flybridgeflybridge.com | Mostly Lead | $100k – $3m$100-250k · $1-3m | — | Specialist | Infrastructure / Developer Tools, Enterprise Software | Massachusetts | $100M | 2025 | Chip Hazard, Jeff Bussgang, Jesse Middleton, Daniel Porras Reyes | hello@flybridge.com | |
| Founder Collectiveverifiedfoundercollective.com | Can Lead | $1-3m | No targetNo Target | Generalist | — | Massachusetts | — | — | Micah Rosenbloom, Amanda Herson, David Frankel, Eric Paley, Dave Bisceglia, Jack Arenas | contact@foundercollective.com | |
| Four Cities Capitalfourcitiescapital.com | Mostly Follow | — | — | Specialist | Infrastructure / Developer Tools, Industrial / Manufacturing, Climate / Energy, Life Sciences, Fintech, Deep Tech | Massachusetts | — | — | Louis Beryl, George Davies, Ben Hutchinson | contact@fourcitiescapital.com | |
| G20 Venturesg20vc.com | Can Lead | $1m – $10m$1-3m · $3M - $10M | — | Specialist | Enterprise Software | Massachusetts | — | — | Bob Hower, Mike Troiano, Bill Wiberg | — | |
| General Catalystgeneralcatalyst.com | Mostly Lead | $1m – $30m+$1-3m · $3M - $10M · $10M - $30M · >$30M | 7–10%7-10% | Generalist | — | Massachusetts | $8B new capital (Fund XII: $4.5B core VC, $1.5B Creation, $2B separately managed accounts) | 2024 | Chris Bischoff, Larry Bohn, Niko Bonatsos, Ken Chenault, Quentin Clark, Joel Cutler, Kyle Doherty, David Fialkow, Paul Kwan, Holly Maloney, Deep Nishar, Trevor Oelschig, Hemant Taneja, Alex Tran, Adam Valkin, Marc Bhargava, Pranay Orugunta, Christopher Kauffman, Genevieve Kinney, Candace Richardson, Johnson Yang, Zak Kukoff, Reva Nohria | gcinfo@generalcatalyst.com | |
| Glasswing Venturesglasswing.vc | Can Lead | — | 7–10%7-10% | Specialist | Deep Tech, Cybersecurity, Enterprise Software | Massachusetts | $200M+ Fund III | 2025 | Rudina Seseri, Rick Grinnell, Kleida Martiro, Vlad Sejnoha, Ali Mahmoud, James Massaquoi | info@glasswing.vc | |
| Global Millennial Capitalglobalmillennialcapital.com | — | — | — | Specialist | Crypto / Web3, Infrastructure / Developer Tools | Massachusetts | USD 100M (GMCL IPO Opportunities Fund; final close) | — | Andreea Danila, Henry Sun, AJ Jena, Vadim Rakitskii | hello@millennialvc.co | |
| Grantham Foundationgranthamfoundation.org | Mostly Lead | — | — | Specialist | Climate / Energy | Massachusetts | — | — | Kevin Tidwell | info@granthamfoundation.org | |
| Gutbrain Venturesgutbrainventures.com | Mostly Lead | — | — | Specialist | Enterprise Software | Massachusetts | — | — | Bob Davoli | — | |
| Hyperplanehyperplane.vc | Mostly Lead | $250k – $3m$250-500k · $500k-1m · $1-3m | — | Specialist | Deep Tech, Infrastructure / Developer Tools, Enterprise Software, Industrial / Manufacturing, Supply Chain / Logistics / Mobility | Massachusetts | — | — | Anthony Tayoun, John Murphy, Samara Gordon, Vivjan Myrto | VivjanMyrto@hyperplane.vc | |
| IDEO CoLab Venturesideocolab.com | Mostly Lead | $250k – $3m$250-500k · $500k-1m · $1-3m | — | Specialist | Crypto / Web3, Fintech, Infrastructure / Developer Tools | Massachusetts | $21M | 2020 | Joe Gerber, Reuben Brama | fundteam@ideo.com | |
| Inflectioninflection.fund | Can Lead | $500K–$2MStated investment range · Official website · https://inflection.fund/portfolio | — | Specialist | Aerospace / Defense, Climate / Energy, Deep Tech, Infrastructure / Developer Tools, Industrial / Manufacturing | Massachusetts | $40 million | — | Alexander Lange, Jonatan Luther-Bergquist | contact@inflection.fund | |
| Innospark Venturesverifiedinnospark.vc | Can Lead | $250k – $3m$250-500k · $500k-1m · $1-3m | 7–10%7-10% | Generalist | — | Massachusetts | — | — | Venkat Srinivasan, Matt Fates, Mark Legare, Jeff Knox, Brent Willess, Max Krause | max.krause@innospark.vc | |
| J2 Venturesj2vp.com | Can Lead | $1m – $10m$1-3m · $3M - $10M | 7–10%7-10% | Specialist | Deep Tech, Cybersecurity, Infrastructure / Developer Tools, Healthtech / Digital Health, Life Sciences | Massachusetts | $250 million | 2025 | Alexander Harstrick, Jonathan Bronson, Christine Keung, Matthew Goldman, Aashka Dave | info@j2vp.com | |
| January Venturesjanuary.ventures | Mostly Follow | $250k – $1m$250-500k · $500k-1m | — | Generalist | — | Massachusetts | $21 million | 2022 | Jennifer Keiser Neundorfer, Maren Thomas Bannon | hello@january.ventures | |
| JDRF T1D Fundt1dfund.org | Mostly Follow | — | — | Specialist | Life Sciences, Healthtech / Digital Health | Massachusetts | $250 million+ AUM | 2016 | Sylvia Tobé, Lucio Iannone, Daniel Flicker, Peyman Hosseinchi, Valerie Su, Morgan Janes, Yash Malliwal | https://t1dfund.org/contact-us/ | |
| Koa Labskoalab.com | Mostly Follow | $100-250k | — | Generalist | — | Massachusetts | — | — | Andy Palmer | associates@koalab.com | |
| LAMA Partners (fka FXP Ventures)lama.vc | — | — | — | Specialist | Cybersecurity | Massachusetts | — | — | Gil Zimmermann, Ron Zalkind, Tsahy Shapsa, Roy Katzenelson | info@lama.vc | |
| LearnLaunch Fund + Acceleratorlearnlaunch.com | Mostly Lead | $100k – $3m$100-250k · $250-500k · $500k-1m · $1-3m | — | Specialist | Education / Future of Work | Massachusetts | — | — | Tetyana Astashkina, Jean Hammond, Matthew J. Rubins, Sagnik Ghosh | accelerator@learnlaunch.com | |
| Link Venturesverifiedlinkventures.com | Mostly Follow | $500k – $10m$500k-1m · $1-3m · $3M - $10M | > 12%> 12% | Generalist | — | Massachusetts | — | — | Dave Blundin, Mike Griffin, Dominic Lloyd, Matt Rita, John Werner, Frazer Anderson, Boaz Fachler, Rachael Harkavy, Peter Diamandis | info@linkventures.com | |
| LiquidMetal Venturesliquidmetalvc.com | — | — | — | Specialist | Life Sciences, Climate / Energy, Deep Tech | Massachusetts | $10 million | 2022 | Ji Zhao, Qiong Ye, Tsz Kwan Lam, Zhu Liang | — | |
| Longwood Fundlongwoodfund.com | Mostly Lead | — | 7–10%7-10% | Specialist | Life Sciences | Massachusetts | — | — | Christoph Westphal, Rich Aldrich, Aleks Radovic-Moreno, Vikas Goyal, Sean O'Connor, Aparaajita Balaji | info@longwoodfund.com | |
| LRVHealthlrvhealth.com | Mostly Lead | $1m – $10m$1-3m · $3M - $10M | 7–10%7-10% | Specialist | Healthtech / Digital Health | Massachusetts | $200 million (Fund V) | 2023 | Will Cowen, Keith J. Figlioli, Josh Flum, Tripp Peake, Lise Courtney D'Amico, Ellen Herlacher, Yoola Adeniji | lrvhealth@lrvhealth.com | |
| MassMutual Impact Investingmassmutual.com | — | — | — | Generalist | — | Massachusetts | $100 million (second MM Catalyst Fund) | 2023 | — | — | |
| MassMutual Venturesmassmutualventures.com | Mostly Lead | $1m – $10m$1-3m · $3M - $10M | 7–10%7-10% | Specialist | Enterprise Software, Fintech, Cybersecurity, Healthtech / Digital Health, Climate / Energy | Massachusetts | — | — | Doug Russell, Eric Emmons, Mark Goodman, Tim Krysiek, Charles Svirk, Kara Burns, Aram Ouligian | — | |
| MassVenturesmass-ventures.com | — | — | — | Specialist | Deep Tech, Climate / Energy, Life Sciences | Massachusetts | — | — | — | — | |
| MCJmcj.vc | Mostly Follow | $100-250k | — | Specialist | Climate / Energy | Massachusetts | >$72M MCJ 2023 | 2023 | David Aronoff, Cody Simms, Yin Lu, Thai Nguyen, Jason Jacobs, Casey Goldstein | info@mcj.vc | |
| Meach Cove Capitalmeachcovecapital.com | — | — | — | Specialist | Food / Agriculture | Massachusetts | — | — | Harris Komishane, Ken Zolot, James Cornell | — | |
| Mendoza Venturesmendoza-ventures.com | Mostly Lead | $500k – $3m$500k-1m · $1-3m | — | Specialist | Fintech, Cybersecurity, Industrial / Manufacturing | Massachusetts | $100M target Fund III ($40M raised) | 2023 | Adrian Mendoza, Senofer Mendoza, Adam Kerr, Aymbre Paige, Ricardo Heredia | partners@mendoza-ventures.com | |
| Meridian Venturesmeridianvc.com | Mostly Follow | $250k – $1m$250-500k · $500k-1m | — | Specialist | Enterprise Software | Massachusetts | $35M Fund II | 2026 | Devon Gethers, Karlton Haney | info@meridianventures.co | |
| Mission BioCapitalmissionbiocapital.com | Can Lead | $25k – $10m$25-100k · $250-500k · $1-3m · $3M - $10M | 7–10%7-10% | Specialist | Life Sciences | Massachusetts | $143.75M raised to date for Fund VI (SEC Form D, Nov. 2025); prior Fund V was $275M | 2024 (Fund VI first sale); 2021 (Fund V) | Robert Blazej, Cassidy Blundell, Zach Collins, Jennifer Griffin, Douglas Crawford, Peter Parker, Steve Tregay, Johannes Fruehauf, Ulrik B. Nielsen, Chaya Patel, Josephine Brysting, Clay Rowland | info@missionbiocapital.com | |
| MVM Life Science Partnersmvm.com | Can Lead | $10m – $30m+$10M - $30M · >$30M | 7–10%7-10% | Specialist | Healthtech / Digital Health, Life Sciences | Massachusetts | >$1B AUM | — | Eric Bednarski, Thomas Casdagli, Kyle Dempsey | — | |
| My Climate Journey Collectivemcj.vc | Mostly Follow | $100k – $3m$100-250k · $1-3m | — | Specialist | Climate / Energy | Massachusetts | MCJ 2023 — $125M target | 2023 | David Aronoff, Thai Nguyen, Yin Lu, Cody Simms, Casey Goldstein | info@mcj.vc | |
| NYBC Venturesnybcventures.com | — | — | — | Specialist | Life Sciences | Massachusetts | $50M commitment | — | Christopher D. Hillyer, Jay Mohr, Meg Wood, Kuan Yu | — | |
| Olive Tree Capitalolivetreecapital.com | Can Lead | $250k – $10m$250-500k · $500k-1m · $1-3m · $3M - $10M | — | Specialist | Deep Tech, Infrastructure / Developer Tools, Aerospace / Defense | Massachusetts | — | — | Nichola Eliovits, Joseph Lissak, Mickael Chane-Du, Johnny Hatem | — | |
| Omega Fundsomegafunds.com | Can Lead | $10m – $30m+$10M - $30M · >$30M | 7–10%7-10% | Specialist | Life Sciences | Massachusetts | $470.0M Fund VIII | — | Eric Cooper, Deirdre Cunnane, Francesco Draetta, Claudio Nessi, Otello Stampacchia, Bernard Davitian, Michelle Doig, Saoussen Ben Halima, Noelle Hutchins, Kurt Kongtong-Gallagher, Vincent Ossipow | info@omegafunds.net | |
| One Way Venturesonewayvc.com | Can Lead | — | — | Specialist | Deep Tech | Massachusetts | — | — | — | info@onewayvc.com | |
| Optum Venturesoptumventures.com | Can Lead | $1m – $30m$1-3m · $3M - $10M · $10M - $30M | 7–10%7-10% | Specialist | Healthtech / Digital Health | Massachusetts | More than $2B AUM across six funds | — | Larry Renfro, Laura Veroneau, Vijay Barathan, Mike Cunningham, George Pantazopoulos, Tom Capon, Jon Sklaroff, Austin Martin, Eliza McGinn, Joe Gentile, Mazen Hammad, Courtney Good, Anna Reilly, Morgan Noonan | hello@optumventures.com | |
| Pillar VCpillar.vc | Mostly Lead | $25k – $10m$25-100k · $100-250k · $250-500k · $500k-1m · $1-3m · $3M - $10M | No targetNo Target | Generalist | — | Massachusetts | — | — | Jamie Goldstein, Sarah Hodges, Tony Kulesa, Parker McKee, Thomas de Vlaam | contact@pillar.vc | |
| PJCpjc.vc | Can Lead | $500k – $3m$500k-1m · $1-3m | — | Generalist | — | Massachusetts | $80.52 million Fund V | 2020 | David Martirano, Matt Hayes | info@pjc.vc | |
| Polaris Partnerspolarispartners.com | Mostly Follow | $500k – $10m$500k-1m · $1-3m · $3M - $10M | — | Specialist | Healthtech / Digital Health, Life Sciences | Massachusetts | — | — | Jon Flint, Terry McGuire, Alexandra Cantley, Brian Chee, Ellie McGuire, Amy Schulman, Chen-Ee Lee, Nil Gural, Manik Kuchroo | partnership@polarispartners.com | |
| Propellerpropellervc.com | Can Lead | $500K–$3MStated investment range · Official website · https://propellervc.com | 7–10%7-10% | Specialist | Climate / Energy, Industrial / Manufacturing, Supply Chain / Logistics / Mobility, Food / Agriculture | Massachusetts | $118 million Fund I | — | Brian Halligan, Devdutt Yellurkar, Steven Fox, Rodrigo Prudencio, Reece Pacheco | hello@propellervc.com | |
| Qiming Venture Partners USAqimingvcusa.com | Can Lead | $1m – $10m$1-3m · $3M - $10M | 7–10%7-10% | Specialist | Life Sciences, Healthtech / Digital Health | Massachusetts | $260 million US Healthcare Fund III | 2022 | Gary Rieschel, Mark Mcdade, Anna French, Colin Walsh, Isaac Ciechanover | — | |
| RA Capital Managementracap.com | Mostly Lead | $3m – $30m+$3M - $10M · $10M - $30M · >$30M | 7–10%7-10% | Specialist | Life Sciences, Healthtech / Digital Health, Climate / Energy, Industrial / Manufacturing, Food / Agriculture | Massachusetts | $10B+ AUM; $120 million Planetary Health Fund | 2025 | Peter Kolchinsky, Rajeev Shah, Zach Scheiner, Jake Simson, Matt Hammond, Derek DiRocco, Josh Resnick, Jeremy Lack, Laura Stoppel, Adam Kaye, Anurag Kondapalli, Tess Cameron, Emily Minkow, Nandita Shangari, Laura Tadvalkar, Jenna Hebert, Megan Lipcsey, Jonathan Pritz, Emory Werner, Alex Miller, Julie Gupta, Peter Balogh, Maxwell DeNies, Fuad Naser, Breanna O'Reilly, Henry Stusnick, Prithviraj Singha Roy, Sahiba Baveja, Davis Buchanan, Tyler Carney, Justin Waney, Eric Wei, Alex Zhang, Kyle Teamey, Brigid O'Brien, Kathryn Meng, Pat Schnettler | request@racap.com | |
| Reflect Venturesreflectventures.com | — | — | — | Specialist | Supply Chain / Logistics / Mobility, Fintech | Massachusetts | — | — | Michel Friedman, Jor Law, Buddy Ye, Maheen Nadeem | inquiries@reflectventures.com | |
| Reinventure Capitalverifiedreinventurecapital.com | Can Lead | $1-3m | No targetNo Target | Generalist | — | Massachusetts | — | — | Edward Dugger III, Shijiro Ochirbat | https://reinventurecapital.com/contact/ | |
| Remiges Venturesremigesventures.com | Mostly Lead | — | — | Specialist | Life Sciences | Massachusetts | US$100M (RDiscovery Fund, LP; additional close; managed by Remiges subsidiary RDiscovery, KK) | — | Taro Inaba, Takaaki Tobaru, Taka Koda, Kazuhiko Nonomura, Kyoko Matsumoto, Naoki Hirayama | — | |
| REMUS Capitalremuscap.com | Mostly Lead | $3m – $30m$3M - $10M · $10M - $30M | 7–10%7-10% | Generalist | — | Massachusetts | — | — | Krishna K. Gupta, John Tincoff, Sasha Hoffman, Cavin Mozarmi | — | |
| Rhapsody Venture Partnersrhapsodyvp.com | Mostly Lead | $500K–$2MInitial check · Official website · https://rhapsodyvp.com/ | 7–10%7-10% | Specialist | Deep Tech, Industrial / Manufacturing, Food / Agriculture | Massachusetts | — | — | Carsten Boers, Jason Whaley, Corrie Kavanaugh, Jessica Freyer, Mike Fuerstman, Robert Newman, Sarah Hammer | contact@rhapsodyvp.com | |
| Safar Partnerssafar.partners | Can Lead | — | 7–10%7-10% | Specialist | Climate / Energy, Deep Tech, Life Sciences | Massachusetts | More than $1 billion AUM | — | Nader Motamedy, Arunas Chesonis, Sahba Vaziri, Greg S. Feldman, Vera Schroeder, Parinaz Motamedy | info@safar.partners | |
| SBXisbxi.com | Mostly Follow | up to $1mUp to $25k · $25-100k · $100-250k · $250-500k · $500k-1m | < 5%< 5% | Generalist | — | Massachusetts | — | — | — | https://forms.fillout.com/t/hWZqg8F4jpus | |
| Seae Venturesverifiedseaeventures.com | Can Lead | $1-3m | 7–12%7-10% · 10-12% | Specialist | Healthtech / Digital Health, Life Sciences | Massachusetts | — | — | Jason Robart, Tuoyo Louis, Arianne Kidder, Erica Murdock, Justin Williams, Karlos Bledsoe, Molly Steinberg, Adeola Adelekan | Seaevc@seaeventures.com | |
| Smith Point Capitalsmithpointcapital.com | Can Lead | — | — | Specialist | Enterprise Software | Massachusetts | $360 million | 2025 | Keith Block, Burke Norton, Christopher Lytle, Brooke Kiley Slattery, Lorenzo Salazar, Sewon Park, Lily Cordover | investors@smithpointcapital.com | |
| Solasta Venturessolasta-ventures.com | — | — | — | Specialist | Life Sciences | Massachusetts | — | — | Derek Yoon, Michael Jeon, Katlyn Gabriel | https://solasta-ventures.com/contact | |
| SSC Venture Partnersverifiedsscventurepartners.com | Mostly Follow | $25-100k | No targetNo Target | Generalist | — | Massachusetts | — | — | Christina Quinn, Duncan Walker, Tom Coburn, Peter Bell, Kudzai Taziva, Bennett Collen, Michael Nardella | https://airtable.com/shrK0iujMics1OtKp | |
| Stage 2 Capitalverifiedstage2.capital | Mostly Lead | $200K–$5MStated investment range · Official website · https://www.stage2.capital/ | > 12%> 12% | Generalist | — | Massachusetts | — | — | Jay Po, Mark Roberge, Anubhav Maheshwari, Daniel Heck, Liz Christo, Mandy Cole, Sakib Dadi, Sean Po | jay@stage2.capital,anu@stage2.capital,liz@stage2.capital | |
| Summit Partnerssummitpartners.com | Mostly Follow | $10m – $30m+$10M - $30M · >$30M | No targetNo Target | Generalist | — | Massachusetts | — | — | Matthias G. Allgaier, David W. Averett, Darren M. Black, Chris Bon, John R. Carroll, Antony C. Clavel, Peter Y. Chung, Andrew J. Collins, Scott Collins, Christopher J. Dean, Mark A. Delaar, Robin W. Devereux, Ali Dowd, Leonard C. Ferrington, Craig D. Frances, Peter A. Francis, Greg S. Goldfarb, Johannes N. Grefe, Matthew G. Hamilton, Adam H. Hennessey, Mark F. Hexamer, Thomas H. Jennings, Chelsea L. Jurman, Michael A. Medici | — | |
| SustainVCsustainvc.com | Mostly Follow | $500k-1m | — | Specialist | Climate / Energy, Healthtech / Digital Health, Education / Future of Work | Massachusetts | — | — | Sky Lance, Tom Balderston, Justin Desrosiers, Eric Chapman, Andrew Cousins, Kendall Bedford | info@sustainvc.com | |
| SV Health Investorssvhealthinvestors.com | Can Lead | — | 7–10%7-10% | Specialist | Life Sciences, Healthtech / Digital Health | Massachusetts | $269M Dementia Discovery Fund 2 | 2025 | Alex Badamchi-Zadeh, Michael Balmuth, Laurence Barker, Jamil M. Beg, Kate Bingham, Andrew Cappetta, Charles Dunn, Tom Flynn, Georgia Frost, Miles Gerson, Eugene Hill, Jean Rivera Irizarry, Christian Jung, Vineela Kanagala, Paul LaViolette, Dirk Landgraf, Greg Madden, Mike Ross, A.J. Rossi, Lennart Spindler, Nikola Trbovic | https://www.svhealthinvestors.com/contact | |
| Tectonic Venturestectonicventures.com | Can Lead | — | 7–10%7-10% | Specialist | Enterprise Software, Infrastructure / Developer Tools | Massachusetts | — | — | Morris Miller, Matthew Rhodes-Kropf, Juan Luis Leungli, Mark Weber | — | |
| The Aligned Fundthealignedfund.com | Mostly Lead | — | 7–10%7-10% | Specialist | Enterprise Software | Massachusetts | — | — | Ariel Winton-Jones | https://www.thealignedfund.com/contact | |
| The E14 Funde14.vc | Can Lead | $25k – $10m$25-100k · $1-3m · $3M - $10M | 7–10%7-10% | Specialist | Deep Tech | Massachusetts | — | — | Calvin Chin, Habib Haddad, Shin Chen | directors@e14fund.com | |
| The Engineengineventures.com | Mostly Lead | $250k – $10m$250-500k · $500k-1m · $1-3m · $3M - $10M | 7–10%7-10% | Specialist | Deep Tech, Climate / Energy, Life Sciences, Healthtech / Digital Health, Industrial / Manufacturing | Massachusetts | $398M (Fund III) | 2024 | Katie Rae, Israel Ruiz, Reed Sturtevant, Ann DeWitt, Michael Kearney, Vinny Beranek, Rachel Field, Deepa Rao, Alaina Hartnett, Ericka Tamayo-Guevara, Sophia Cohen | info@engineventures.com | |
| Two Lanterns Venture Capital2l.vc | — | — | — | Generalist | — | Massachusetts | — | — | John Harthorne, Michal Gilon-Yanai, Lily Toto | contact@2L.vc | |
| Underscore VCverifiedUnderscore.VC | Mostly Lead | $500k – $3m$500k-1m · $1-3m | 7%+7-10% · 10-12% · > 12% | Generalist | — | Massachusetts | — | — | Brian Devaney, Chris Gardner, Lily Lyman, Richard Dulude, James Orsillo, Gabrielle McCarthy | hello@underscore.vc | |
| Venture Guidesventureguides.com | Can Lead | — | — | Specialist | Infrastructure / Developer Tools | Massachusetts | US$262.5M (Fund II; single close) | — | Anton Simunovic, Ben Nye | IR@ventureguides.com | |
| Vestigo Venturesvestigoventures.com | Mostly Lead | — | — | Specialist | Fintech | Massachusetts | — | — | Dave Blundin, Mark Casady, Ian W. Sheridan, Frazer Anderson, John Werner | info@vestigoventures.com | |
| Vinyl Capitalvinyl.vc | Mostly Follow | $500k – $3m$500k-1m · $1-3m | — | Specialist | Commerce / Marketplaces, Infrastructure / Developer Tools | Massachusetts | — | — | TJ Mahony, Travis Kirk Lowry, Jake Cohen | — | |
| Visible Handsvisiblehands.vc | Mostly Follow | $100-250k | — | Generalist | — | Massachusetts | — | — | Yasmin Cruz Ferrine, Daniel Acheampong, Justin Kang | daniel@visiblehands.vc | |
| Visible Venturesvisibleventures.com | Mostly Follow | $250k – $3m$250-500k · $500k-1m · $1-3m | No targetNo Target | Specialist | Education / Future of Work, Fintech, Healthtech / Digital Health, Consumer | Massachusetts | — | — | Lori Cashman, Neidelyn Pina, Donald Finley, Athena Zhang, Madeline Murphy | https://visibleventures.com/pitch/ | |
| Volition Capitalvolitioncapital.com | Mostly Lead | $10m – $30m+$10M - $30M · >$30M | 7–10%7-10% | Generalist | — | Massachusetts | $950M Fund VI | — | Sean Cantwell, Larry Cheng, Roger Hurwitz, Tomy Han, Jim Ferry, Kyle Howard-Johnson, Melanie Nabar, Tiger Henderson, Emily Pawlak, Michael Brannan, Isabelle Tashima, Sinjon Goldberg, Carolyn Woll, Ella Steinhilber, Danielle Brown, Justin Chung, Trevor Eckler, Cassidy Piersiak, Nikki Schwenk, Zane Salameh, Juliet Fitzgerald, Hannah Ditmars, Chad Kemmerer, Emily Yoon, Louis Cornett, Simon Kushkov | info@volitioncapital.com | |
| VXI Capitalvxicapital.com | — | — | — | Specialist | Climate / Energy, Deep Tech | Massachusetts | — | — | — | — | |
| W Health Ventureswhealthventures.com | Can Lead | $1m – $10m$1-3m · $3M - $10M | — | Specialist | Healthtech / Digital Health | Massachusetts | — | — | Dr. Pankaj Jethwani, Gaurav Porwal, Tushar Sadhu | hello@whealthventures.com | |
| Waterline Ventureswaterlineventures.com | Mostly Follow | — | — | Specialist | Healthtech / Digital Health | Massachusetts | — | — | Robbie Greenglass, John Curtin, Katharine French | info@waterlineventures.com | |
| Wave Functionwavefx.com | — | — | — | Generalist | — | Massachusetts | — | — | Al Peters | al@wavefx.com | |
| Will Ventureswillventures.com | Mostly Lead | — | 7–10%7-10% | Specialist | Consumer, Healthtech / Digital Health, Gaming / Media / Sports | Massachusetts | — | — | Brian Reilly, Isaiah Kacyvenski, Ben Gardner, Kushaan Ahuja, Aaron Miller, Yash Gupta | — | |
| Workshop Venture Partnersworkshop.dev | — | — | — | Specialist | Education / Future of Work, Climate / Energy | Massachusetts | — | — | Chad Laurans, Eleanor Laurans, Mike Berlin, Eddie Branchaud, Jason Carter | — | |
| Xontogenyxontogeny.com | Mostly Follow | — | — | Specialist | Life Sciences | Massachusetts | — | — | Chris Garabedian, Fred Callori, Gianna Hoffman-Luca, Takeru Furuya, Thien Nguyen, Jayanth Batchu | info@xontogeny.com | |
| Yael Capital Management Limitedyaelcapital.com | — | — | — | Specialist | Life Sciences, Deep Tech | Massachusetts | — | — | — | — | |
| Yonjin Ventureyjventure.com | Mostly Follow | — | — | Specialist | Life Sciences | Massachusetts | — | — | Daguang Wang | — |
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